Approximating dementia prevalence in population‐based surveys of aging worldwide: An unsupervised machine learning approach
Abstract
Introduction
Ability to determine dementia prevalence in low‐ and middle‐income countries (LMIC) remains challenging because of frequent lack of data and large discrepancies in dementia case ascertainment.
Methods
High likelihood of dementia was determined with hierarchical clustering after principal component analysis applied in 10 population surveys of aging: HRS (USA, 2014), SHARE (Europe and Israel, 2015), MHAS (Mexico, 2015), ELSI (Brazil, 2016), CHARLS (China, 2015), IFLS (Indonesia, 2014–2015), LASI (India, 2016), SAGE‐Ghana (2007), SAGE‐South Africa (2007), SAGE‐Russia (2007–2010). We approximated dementia prevalence using weighting methods.
Results
Estimated numbers of dementia cases were: China, 40.2 million; India, 18.0 million; Russia, 5.2 million; Europe and Israel, 5.0 million; United States, 4.4 million; Brazil, 2.2 million; Mexico, 1.6 million; Indonesia, 1.3 million; South Africa, 1.0 million; Ghana, 319,000.
Discussion
Our estimations were similar to prior ones in high‐income countries but much higher in LMIC. Extrapolating these results globally, we suggest that almost 130 million people worldwide were living with dementia in 2015.
Authors
Laurent Cleret de Langavant, MD, PhD
Neurologist