Creative cognition in frontotemporal dementia and brain health

Trends in neurosciences

Trends Neurosci. 2026 Nov 7:S0166-2236(26)00231-6. doi: 10.1016/j.tins.2026.10.009. Online ahead of print.

ABSTRACT

Creative cognition is central to human thought and is affected by brain disease. Recent findings by Altmayer and colleagues link creative impairment in frontotemporal dementia to rostral prefrontal functional differentiation. These findings motivate a framework for investigating network coordination, circuit physiology, experience-dependent plasticity, and bodily and social regulation in creativity and health.

PMID:42998906 | DOI:10.1016/j.tins.2026.10.009